Surova N. System for prediction of human prediabetes condition development

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0414U004964

Applicant for

Specialization

  • 05.11.17 - Медичні прилади та системи

14-11-2014

Specialized Academic Board

К 05.052.06

Vinnytsia national technical university

Essay

The object of study is the process of early diagnosis and prediction of the emergence and development prediabetes human condition. The aim is to improve the efficiency and accuracy of prediction of the emergence and development of the prediabetes human condition based on the method and system of forecasting prediabetes human condition. Methods: method of mathematical modeling; theoretical and experimental methods of system analysis; methods of biotechnical system theory; functional diagnostics; clinical and experimental studies. First a comprehensive mathematical model for the diagnosis and prediction of the human condition with signs of diabetes is constructed, which forms the general prediction, based on corrected, noncorrected partially corrected risk factors of diabetes and defuzzification intervals, using for monitoring the emergence, development and prediction of diabetes (diabetes mellitus) mathematical model for fuzzy sets, and, in case of the ambiguous nature of the forecast, use for it's clarifying probabilistic model based on Bayes' formula, improve reliability prediction of diabetes; first method of forecasting diabetes human condition is proposed, which is based on the regularities of form FIG blood sugar levels and dependence prediabetes state on glucose concentration in the air exhaled by man presented as a series of logical resulting steps of study, assessment of the patient's condition and making decision; approach to developing diagnostic tests is improved, that is built on the model of expert system with knowledge base, which includes rules and factors varying degrees of correction individually for each patient, which allows us to calculate the probability of prediabetes human condition within 5 next years. Practical results are as follows: project of the medical and technical requirements and forecasting system of prediabetes human condition, the main constituent of which are subsystems study and evaluation of state and decision-making are designed. Diagnostic sensor of determination of glucose in the blood in the air exhaled by the patient is developed. Database is proposed in the form of two-dimensional tables of relational type of management system. The degree of implementation - the results of the thesis are introduced in Vinnytsia Oblast Clinical endocrinology center (m. Vinnitsa), in the educational process of the Department of biomedical devices Vinnytsia National Technical University (m. Vinnitsa). The field (area) of use - medicine.

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