Bogatskyy S. Dynamics of andrology semiotics in the evaluation of the clinical course of primary hypogonadism.

The work examines the characteristics of physical, sexual development and functional state of the pituitary-gonadal males with primary hypogonadism pubertal and post-pubertal periods of sexual development. The study involved 145 males aged 12 to 43 years with primary hypogonadism. Teens puberty 30 people aged 12-17 years and 115 post-pubertal males aged 18-43 let.Kontrolnuyu group consisted of 44 male individuals of different age groups without a history of hypogonadism. The results of the survey confirm the presence otstovaniya in sexual development (20.6%) patients with primary hypogonadism poslepodrostkovogo period (18-19 years) to 2.5 years, and in patients puberty at 0.5 years, which was accompanied by absolute and relative androgenic deficits that occur with disorders of the Leydig cells, which leads to a decrease in the level of T and a compensatory increase in the level of LH and FSH increase in the concentration of serum is the result of the seminiferous tubules of defeat, to continue in adolescence and puberty phase in all phases poslepubertatnye poslepodrostkovogo transitional period and the period of mature sexuality sexual development, progression is characterized by changes in the genital and gonadotropin-releasing hormone, which result in delayed sexual development and reproductive function. Analyzing the data of phenotypic development in patients with primary hypogonadism should be noted that significant deviations from acceptable standards in terms of assessing the development of the phenotype in patients with all phases of puberty and in the early phase of post-pubertal period.