Object of research: the psychological characteristics of a business entity.Subject of research: psychological predictors of success and self-realization for women in business.Methods of research. To address research questions were used: theoretical methods (problem - logical method, induction, abstraction, generalization, systematization, modeling) that were used to summarize the theoretic-methodological foundations and experimental data of the research; empirical methods (the method of "transverse slice" method of psychological diagnostics and methods of mathematical data processing (descriptive statistics, correlation analysis, cluster analysis, one-factor analysis of variance (ANOVA), discriminant analysis, Wilcoxon's T-criteria., N. Kruskal - Wallis' criteria. The calculations were performed using the package of applied computer programs universal processing tabular data in Microsoft Excel XP and the statistical analysis package SPSS for Windows 17.0 v). Method of psychological diagnostics of the survey included: a modified version of interpersonal diagnosis of T. Leary (DIR, L. N. Sobchik); "the Scale of reactive and personal anxiety" (C. D. Spilberger); method of Diagnosis of achievement motivation" (A. Mehrabian); the method "Test of resilience" (D. A. Leontiev, E. I. Rasskazova); the method "Test of life-meaningful orientations (WCS, D. A. Leontiev); questionnaire "Motivation to success and fear of failure" (A. A. Rean); technique of Diagnostics of socio-psychological personal attitudes in need - motivational sphere" (E. F. Potemkin), the method of stress-resistance and social adaptation (T. Holmes and R. Rage); K. Thomas' test in the modification of N. In.Grishina for Diagnostics of preferred style of behavior in conflict situation. Scientific novelty of the results is that for the first time were: demonstrated the differences of socio-psychological characteristics of successful women and men entrepreneurs; conducted comparison of the psychological profiles of successful and potential entrepreneurs; identified predictors of success in entrepreneurial activity by gender; showed the differences in the characteristics of entrepreneurs, depending on the duration of professional activity; installed features intrapersonal congruence among entrepreneurs; showed the differences in the structure of the relationships of variables in the subjects of entrepreneurial activity; clarified the specifics of meaningfulness of life, time perspective, motivation, strategies of behavior in conflict situations among entrepreneurs based on gender and length of professional activity; - clarified the types of interpersonal relations that do not contribute to the career of an entrepreneur. The practical significance of the research is that the results of the study of psychological predictors of success and self-realization of women in entrepreneurial activity can be used in lecture courses: "Differential psychology", "Psychology of work" and courses "Psychological characteristics of business leaders", "Rehabilitation of businessmen" for students of psychological departments, in the practice of a psychologist while working with staff.Scope institutions of higher education, psychological services.