Zahoruyko R. Minimally invasive treatment of inflammatory processes of the upper urinary tracts

3. The dissertation is dedicated to the increasing of the effectiveness of the treatment of the obturative(obstruction) pyelonephritis of the parenchyma with the destruction and without it by the improvement of the methods of their minimally invasive treatment. The dissertation deals with the results of the treatment of 264 patients with inflammatory processes of the upper urinary tracts, obturative pyelonephritis of the kidney parenchyma with the destruction and without it and infections kidney cysts. From 264 patients the following groups have been formed: the first comparison group - 49 patients with infiltrative inflammatory processes of the kidneys, without the deterioration of the urine passage; the second comparison group - 109 patients with obturative pyelonephritis on the ground of urine stone disease without the destruction of the kidney parenchyma; 106 patients belonged to the main group with the destruction of the kidney parenchyma with obturative pyelonephritis, 21 patients being with the purulent kidney cysts without the deterioration of the urine passage and 85 patients with obturative pyelonephritis: 48 with the concrements of urinary tracts and 37 with the concrements of the kidneys. General clinic, laboratory, radiographically (examining and excretion urography, retro and antegrade pyelography, computer tomography have been carried out.) Leucocytes index of intoxication has been calculated for the estimation of immune response and the presence of endogenous intoxication. According to the results of the researches scientific data of the pathogenesis of inflammatory diseases of the upper urinary tracts have been substantiated. It has been proved that diabetes - 44,9 per cent and extrarenal purulent hotbeds (furunculosis) - 36,7 per cent, though in every fifth case their aetiology being uncertain, have been true factors promoting the development of inflammatory kidney disease in case of the absence of urine stone disease. Microbiocenosis of the urine has been studied, domination of the conventional -pathogenic abnominal and hospital bacterial symptoms (shtums) has been observed: E. coli - 42 per cent, Klebsiella pneumonia - 18,4 per cent, Enterococcus - 16,3 per cent, Staphylococcus - 8,2 per cent, P. aeruginosa - 8,2 per cent, Proteus - 6,1 per cent.