Shendryk V. Treatment of the complicated erysipelas forms with use of surgical methods and nitrogen oxide

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0417U002975

Applicant for

Specialization

  • 14.01.03 - Хірургія

26-09-2017

Specialized Academic Board

Д 26.613.08

Essay

The thesis is devoted to research of features of early surgical treatment, nitrogen oxide use, development of an algorithm of the diagnostic and treatment, prevention of progressing of a disease and development of complications. On the basis of treatment results comparison of patients with use of traditional methods and patients who were treated complexly with use of surgical methods, nitrogen oxide and an immunomodulator it has proved that complex treatment with use of the offered methods is characterized by momentary improvement of a clinical course of the disease, lack of cases of progressing of the erysipelas and complications which often conduct to an invalidism. There have conducted immunologic researches and has studied influence of an immunomodulator on immunity. There have showed that complex treatment causes minor changes of immunity in patients with mild severity of the erysipelas (р>0,05) and authentically contributes to normalization of immunity at patients with average and heavy degree. Inclusion in complex treatment of an immunomodulator positively influences the immune status of patients with erysipelas with any severity. There have developed legible indications to early surgical treatment of all forms of the erysipelas. Has developed the algorithm of diagnostic and choice a method of treatment at patients with different forms of erysipelas. In the main group surgically treated 53 patients (56,9 %), in the comparison group - 23 (19,2 %). Complicated forms increased in 3 times, surgical treatment in the main group - by 37,7 % (in 2,3 times). In dissertation work have showed results of efficient early surgical treatment of different forms of the erysipelas and NO-therapy in complex treatment with use of an immunomodulator that allowed to prevent a progress of the disease and to develop of complications. Pain decreases in (2±1,2) days (anesthetizing medicines are not necessary), intoxication considerably decreases (bodies temperature decreases to normal indexes in (2±1,2) days), the term of treatment reduce by 7,3 days.

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