Matvieiev S. Thrombolytic therapy for the pulmonary embolism treatment

From 146 patients included in the study, for the final diagnosis of pulmonary embolism (PE), 97 (66,4 %) originally were performed multidetector computer tomography of the chest (MDCT) 48 (32,8 %) performed Pulmonary Angiography (PAG). During 3 years, 11 (7,9 %) cases of long-term relapse of the PE were recorded. All recurrences occurred in the intervals from 1 to 7 years after the first episode of the PE, and in 10 (6,8 %) cases after discontinuation of treatment or inadequate dose of anticoagulants. In all 10 (6,5 %) patients examined by PCR method of diagnosis of variant genes of thrombophilia, violations were detected to varying degrees. Thus the program for prevent reccurent PE, which include necessary thrombophilia investigation before continue or break anticoagulants was performed. The usіng of this program, led to a tendency to reduce the frequency of recurrent episodes (p = 0,08).