The object of research: processes, influencing the formation of regulatory mechanisms of organism functional state and organs of the immune genesis of quail of breed “Pharaoh” during critical physiological periods of ontogenesis and in separate stages of the adaptive syndrome when the dietary supplement "Primix Bionorm-K" and the feed supplement "Biovir" are added to the ration.
The purpose of research: to find out of the immuno-physiological state of the quails organism of the “Pharaoh” breed in the critical periods of postnatal ontogenesis and features of regulatory mechanisms of immunological adaptation of their organism in some stages of the adaptative syndrome when it is included in the ration of the biologically active feed supplement "Primix Bionorm-K" and the feed supplement "Biovir".
Diagnostic techniques: clinical and physiological, hematological, immunological, microbiological, morphological, histological, statistics.
Scientific novelty: For the first time, differences in the mechanisms reflecting the development of the adaptive syndrome in organism of the young quails of the “Pharaoh” breed of industrial cultivation for the influence of complex technological stress during the period of early puberty. It was shown that at the stage of anxiety and resistance in quail of early age, the development of stress does not affect the processes of hemopoiesis, but is characterized by a decrease in the state of nonspecific resistance and immunological reactivity, and also does not exert destructive influence on the structure of central and peripheral organs of immunogenesis. It was found out that during the repeated exposure of the stress stimulus in the quail there is an active reaction from the side of the hypothalamic-pituitary adrenocorticotropic system, which leads to a decrease in the oxygen-transport function, activation of the immunological link in blood defense, reduction of functional reserves of central and peripheral organs of immunogenesis in a productive egg-laying period. The installed changes indicate the power of the stress stimulus, indicate the role of stress-implementing systems (neuroendocrine and immune) at different stages of the formation of adaptive syndrome and can serve as criteria for assessing the mechanisms of development of adaptive reactions and the functional state of the poultry organism, in general, to the action of a complex of stimuli in conditions of industrial stress. The component of the dynamic development of quail production technologies is the inclusion of the “Primix Bionorm-K” and “Biovir “ supplements in the ration was established, which have a positive effect on the processes of hemopoiesis, the functional state of organism resistance against the elimination of microbiocenosis disorders, contribute to increased productivity and conservation of livestock. Better adaptive effect on the development of stress in the organism of the quail of industrial cultivation was found during the feeding with “Primix Bionorm-K”, which allows to use an additive to increase the activity of protective mechanisms of the organism of this species of poultry and maximize the use of genetic potential in the development of an effective anti-stress prevention scheme.
Was offered: To increase the immunophysiological adaptation of the organism of the young quail of the breed "Pharaoh" industrial cultivation technology for the actions of a complex of stress stimuli it is recommended to use an adaptation syndrome in separate stages BAFS "Primix Bionorm-K" and the feed supplement "Biovir" from 5 to 30 day old poultry according to the instructions. According to indicators of development of adaptive reactions and economic efficiency it is expedient to use in the poultry ration BAFS "Primix Bionorm-K".
Were implemented: The main provisions of the dissertation work are used in scientific research and educational process on the course "Normal and Pathological Physiology", "Histology", "Immunology and Microbiology" for students of the Faculty of Veterinary Medicine of National University of Bioresources and Nature Management of Ukraine, Bila Tserkva National Agrarian University, Sumy National University, Dnipro State Agrarian and Economic University, Poltava State Agrarian Academy, Podilsk State Agrarian and Technological University.
