Fakhrutdinova T. Prophylaxis of obstetric and perinatal pathology at women with an excess increase of body weight during pregnancy

Dissertation work is devoted to depression of obstetric and perinatal complications at pregnant women with an excess increase of body weight during pregnancy on the basis of studying of clinical-functional, endocrinologic, metabolic, morphological features of condition of fetoplacental complex and development of advanced algorithm of treatment-and-prophylactic actions. Interrelations between a lipide exchange and level of biochemical and hormonal indicators of a blood in different durations of gestation are established. It is thus shown that in the I trimester communication of percent of fatty body weight with basal and insulinemiya that correlates, respectively, with an indicator of an insulinorezistation of Homo, and also concentration of cholesterin is moderated. In the second trimester except basal insulinemiya and insulinorezistentnost trace positive communication with triglycerides and negative with lipoproteins of high density. At the end of pregnancy it is taped communication of percent of fatty body weight only with basal secretion of insulin and Homo's index that remains and after a delivery. It is presented role of pathological increase of body weight during pregnancy in genesis and clinical current of preeclampsia, and also further perinatal pathology. Need of improvement of algorithm of prophylaxis of obstetric and perinatal complications at women with pathological increase of body weight is scientifically proved during pregnancy. The established comparative aspects of premorbidal background, existence of an accompanying genital and somatic case rate, the clinical course of pregnancy and labors at women with different increase of body weight during pregnancy. It is shown the general and distinctive moments of development of preeclampsia and the subsequent perinatal pathology is at women with pathological increase of body weight during pregnancy. Features of condition of newborns and their post-natal adaptation depending on the size of an increase of body weight are presented during pregnancy. The algorithm of diagnostic and treatment-and-prophylactic actions for depression of frequency of obstetric and perinatal pathology at women with pathological increase of body weight is improved and introduced during pregnancy on the basis of stage-by-stage carrying out psychological and medicamental correction