Sheremet M. Neurohumoral predictors of the efficiency of antihypertensive therapy in patients with resistant arterial hypertension

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0419U001397

Thesis Registration Form

0419U001397.pdf

Applicant for

Specialization

  • 14.01.11 - Кардіологія

19-06-2019

Specialized Academic Board

Д26.616.01

Essay

Clinical, biochemical and neurohumoral features of patients with resistant arterial hypertension (RAH) were studied. A comparative analysis of the response to treatment with spironolactone, eplerenone, nebivolol and moxonidinе showed that the most effective 4th component of therapy for these patients are spironolactone and eplerenone. Based on the comprehensive evaluation of basal biochemical parameters, activities of low-grade inflammation and neurohumoral system of blood pressure regulation the predictors of efficacy of the 4th medicine for treatment of RAH patients were determined. Approaches to diagnosis of pseudoresistant and true RAH were improved.

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