Abdulfatah A. Prognosis and prevention of development early postoperative complications for patients with Benign Prostatic Hyperplasia after Transurethral Resection of the Prostate.

The work is dedicated to solving the actual problem in clinical urology - to improve the results of transurethral resection of prostate (TURP) by prediction the early postoperative complications in patients with benign prostatic hyperplasia (BPH).The study includes two components - clinical and epidemiologic. The second one was the precondition of the first. The data of the official statistics during 2011 - 2016 stated: an increase in the incidence of BPH by 7% in Kyiv-city, which is higher than the average Ukrainians, especially among men of the working age - by 25.6% and 1.7% in the whole of Ukraine among men of the retirement age; a low percentage of dispensary (40 - 53%), growth of operated-on (by 22.1% and 11.4%, respectively); an increase in the duration of hospitalization (by 24.0%) with a mortality rate of 0.42 - 0.5%. The clinical component is based on the analysis of the data of the examination and treatment of the TURP (mono- and bipolar) of 266 patients, 141 of whom were hospitalized urgently, 125 - scheduled, according to which two groups were formed.64.7% of patients had EPOC (in 48/2% - one, in 29.0% - two, in 16/0% - three and in 5.5% four - five).By degree of gravity according to the classification of Clavien-Dindo: I - 90.3%, II - 1.2% and III - 7.5%. There were traced their features by frequency and severity depending on the type of hospitalization, the variant of the TURP, clinical data. The risk factors of the unfavorable course and development of the EPOC were revealed. After statistical analysis, 12 factors with 25 features were selected and their informative significance was determined.According to them, two prognostic cards (for in-patient and out-patient-clinic stages) were proposed to determine the probable development of the EPOC BPH, as well as the optimal timing of surgical treatment. Two groups were made with different degrees of risk of EPOC possibility: the minimum and maximum, were set the limit values of the coefficient, representing the sum of marks of signs that are observed in the patient at the time of the survey. The algorithm of action on each of them is offered.