The dissertation is devoted to the rationalisation of the use of sensory deprivation in the treatment of patients with neurogenic salivary disorders. eurogenic salivary disorders in Ukraine reaches 2-3% among dental diseases, and disorders of the autonomic nervous system (ANS) with salivary gland dysfunction – reaches 15 to 40%. As a rule, these disorders are secondary and develop because of chronic stressful situations that are quite common these days. The regulation of daily salivation depends on the activity of autonomic nervous system and which branch (sympathetic or parasympathetic) is currently prevails. Normally, reflective secretion of saliva is proceeds with the predominance of parasympathetic impulses, which causes the intensity of saliva secretion and vasodilation - as part of the secretory process. The high level of psycho-emotional overloading leads to mental and physical health deterioration, which is connected to the dysregulation of the ANS, which means persistent disturbance of balance between excitatory and deceleration mechanisms. On this phase the study of ANS conditions, its neurotransmitter section and the psycho-emotional conditions in the pathogenesis of neurogenic salivary disorders remains an issue of particular relevance and importance. Conservative therapy remains the main treatment method for patients with neurogenic salivary disorders. The pharmacological treatment for patients with this pathology does not always lead to the desired result. To complete the tasks 30 practically healthy people (volunteers) were examined: 17 men and 13 women in age from 25 to 43. These indicators have been studied: sialometric indicators, adrenaline indicators, norepinephrine indicators, dopamine indicators, hormone melatonin indicators and bioelectrical activity of the brain. The neuropsychological survey was conducted (method SAN and «SF-36 Health Status Survey»). The condition of the autonomic nervous system – vegetative tone, vegetative reactivity and vegetative maintenance of activity were analysed. The use of sensory deprivation in volunteers has shown that this technique does not cause side effects, has a positive influence on the autonomic nervous system and the psycho-emotional condition, which makes it possible to use for neurogenic salivation impairment. The course of treatment lasted 10-15 sessions in every 2 days, the duration of the session is 45-60 minutes.
Thereby the applying of sensory deprivation to volunteers did not cause any negative side effects, has only positive influence on VNS and psycho-emotional condition of patients, which allowed us to conclude that it is advisable to use this method of treatment for patients with neurogenic salivary disorders. The result of the second stage of research was data obtained in the survey of 50 patients (28 men and 22 women) aged 25 to 43 years, disease duration from 2 to 6 years. All patients were examined as well as volunteers before and after treatment. This group of patients was divided into 2 subgroups: the first one - which was carried out complex conservative therapy - 20 people, the second one - which was carried out sensory deprivation. The course of treatment was 10-12 sessions in every 2 days for 45-60 minutes. The obtained results showed that sensory deprivation in most cases restores the salivary glands activity, normalises the dynamics of the autonomic nervous system and its neurohormonal branch (adrenaline, noradrenaline, serotonin, dopamine) and excretion of melatonin, improves brain bioelectric activity and neuropsychological indicators unlike conservative treatment. Conducted clinical studies conclude that the use of sensory deprivation has been advisable not only for patients with neurogenic salivary disorders, but also for patients with vegetative-vascular dystonia, sleep disorders and asthenic disorders. Thus, unlike traditional treatment, in most cases sensory deprivation leads o normalisation of clinical symptoms, promotes the realisation of dynamic homeostasis in the system of intra-daily rhythm. Restoration of bioelectric activity indicators in brain after a course of sensory deprivation in patients with neurogenic salivation disorders is the result of the positive influence of this treatment method on the depth brain structures. Traditional therapy also noted a positive dynamic but it did not contribute to the full restoration of EEG.