Omelchuk O. Physiological State Laying Hens Under the Influence of Nanoacquachelate Solutions of Selenium, Zinc and Vitamin E

The dissertation is devoted to the experimental substantiation of the use of solutions of selenium, zinc and vitamin E and their influence on the physiological state and parameters of blood, metabolism of proteins, lipids, minerals, activity of individual enzymes of the blood and digestive organs after exposure to above mentioned drugs. In the dissertation, in accordance with the set goal, a theoretical generalization and a new solution of the scientific problem are given, which is presented in new scientific data on the effect of nanoacquachelate solutions of selenium, zinc and vitamin E on indicators of protein metabolism, lipids and activity of serum enzymes in laying hens. The effect of the applied drugs on the activity of amylolytic, proteolysis and lipolytic digestive enzymes in the blood, gastric gland, liver, pancreas of the small and large intestine, as well as th e activity of certain enzymes that affect the mineral metabolism in the chicken was studied. The features of protein metabolism and its possible changes were studied by adding of selenium, zinc, and vitamin E nanoacqualates to laying hens, investigating the content of amine nitrogen and uric acid in the serum of laying hens. The level of amine nitrogen in chickens was the same before the experimental period, and the chickens of the experimental groups on the 90th day decreased compared with control, the concentration of uric acid on the 30–60th day of the study in the experimental groups was less than in the control group (p<0.05). It is known that uric acid is one of the ultimate metabolites of nitrogen metabolism in the body, it is about 90 % of all nitrogen excreted in the body, and therefore the synthesis and excretion of uric acid in chickens is one of the regulators of nitrogen balance. The results of the studies indicate the efficiency of the use of selenium, zinc and vitamin E nanoacquachelate to improve the physiological state of laying hens and increase their egg productivity. A method of increasing egg productivity of laying hens by the action of selenium, zinc nanoacquachelate and vitamin E has been developed.