Syrovniev H. Genes ECR F18/FUT1 and ECR F4/MUC4 and their effect on the quantіtatіve traits of pigs in a closed population

The thesis is devoted to study the genetic structure of pigs of the Ukrainian meat breed intrapopulational type of Dnepropetrovsk agricultural Institute selection for genes alpha fucosyltransferase-1 (FUT1) and mucin 4 (MUC4), which associated with resistance to colibacteriosis and the relationships between animal genotypes and performance. The frequencies of alleles and genotypes of FUT1 and MUC4 genes were determined using the PCR-RFLP method. In the population polymorphism for all alleles of genes FUT1 and MUC4 was founded, but their distribution in interpopulation groups is heterogeneous. The studied population of pigs on the FUT1 gene is characterized by a frequency of 0,29 of the desirable allele A. In the inbred group of animals, the frequency of the desirable allele A is 0,20. Among inbred animals the genotype GG (0,71) prevails, and among outbred animals – AG (0,63). A significant part of the animal population on the MUC4 gene is represented by the desirable genotype GG (0,30). The inbred line of pigs is characterized by a high concentration of the allele G – 0,72 and the absence of animals with the CC genotype. The genetic structure of pig lines and families of FUT1 and MUC4 genes was determined. The analysis of genetic relationships between families and lines in the studied population of pigs is carried out and the dendrogram of genetic relationships is constructed. The influence of the genotype of parental forms on genes FUT1 and MUC4 on the processes of reproduction, safety and piglets growth in the early postnatal period in comparison with traditional zootechnical methods was studied.