Pavlenko V. The Role of Cortex and Subcortex Aminergic Structures in Organization of Voluntary Behavioral Act

Object of research - brain mechanisms of control under intentional behavior in animals and human; goal - to discover the role of aminergic systems of brain stem and neuronal neocortex systems in organizing the whole behavioral act including self-initiated movements; methods - registering of movement parameters, impulse neuronal activity and evoked EEG-activity of brain in animals and in human; theoretical and practical results - neurophysiological mechanisms of interaction of associative cortex and sub-cortex aminergic structures in providing control under intentional behavioral acts analyzed; novelty - first elaborated the changes in activity of aminergic neurons in substantia nigra, locus cereleus, dorsal and central nuclei raphe during realization of time-conditioned self-initiated behavioral act; first discovered (1) the positive correlation between the reaction intensity of aminergic neurons developing during movement act preparation and the speed of conditioned movement and (2) the negative correlation between intensity of background neuronal activity, and interval duration between self-initiated movements; first demonstrated the connection between variability of EEG-potentials amplitude parameters and individual psychological traits; first discovered the positive correlation between attention level and amplitude parameters of EEG-potentials components in children.