Garmash O. Clinical and functional statement of the differentiated application of physical factors in resort medical treatment of children with the inflammatory diseases of joints

The dissertation is devoted to the ground of pathogenetic principles of improvement of the differentiated methods of complex physical factors application in resort medical treatment of children with reactive and juvenile rheumatoid arthritis on basis on clinical and functional study of complex evaluation of the disorders in the organism basic systems. Distinctions in levels of electrogenesis in muscles and peripheral circulation in lower extremities of children with reactive arthritis (further, ReA) were exposed, which demonstrated the functional character of changes, unlike more distinctive disorder caused by severity and duration of inflammatory process in juvenile rheumatoid arthritis (further, JRA). The dysfunction of endothelium in children with ReA and JRA was discovered: decline of the NO2 level, increase of endothelium -1, synthase, NO3 in the blood whey at patients with JRA. Prescription of differentiated methods of laser therapy was researched and proved efficient, which is treating the staggered joints, additionally stimulating reflex areas, points of acupuncture or vascular bunches, together with peloid applications or chloride sodium baths. Distinctions in shaping medical treatment effect were disclosed: during peloid application and laser therapy - vasoconstrictors effect with further pressuring action; while balneotherapy combined with laser therapy resulted in predominance of vasodilatation effect. Long-term results (after one year) demonstrated the absence of intensified inflammatory process at ReA patients and three-times decline of frequency and intensity of inflammations at JRA patients.