Akhaladze M. Human aging rate, health status and viability being evaluated from biological age assessments

Українська версія

Thesis for the degree of Doctor of Science (DSc)

State registration number

0507U000528

Applicant for

Specialization

  • 14.03.03 - Нормальна фізіологія

25-09-2007

Specialized Academic Board

Д 26.551.01

Essay

Object of study: random and nonrandom samples (clinical groups), populations from various parts of Ukraine. The purpose of research: Study of quantitative and qualitative characteristics of the aging along the following four directions: populational, clinical, professional and prognosticating. Methods of research: clinical, instrumental, statistical. Theoretical and practical results, novelty of the investigation: It has been found that tempos of ageing play an essential role in the formation of life duration of populations. As has been shown by the author, there is no equal relationship between ageing rates and chronic pathology. Evidences have been received to the effect that the mechanisms of ageing, as such, and the mechanisms of this or other chronic pathology onset can be both, coincident in their essence and different, while accelerating or not influencing the tempo of human organism's ageing. It has been proved that long-term observations (on the basis of biological age assessment) over the workers of various professions, who have been working under different industrial conditions, are highly informative with respect to prognostication of the dynamics of their health status. Acceleration of ageing due to ionizing irradiation exposure has been shown to be joined with earlier chronic pathology onset, especially in younger age individuals. From the data of retrospective analysis of biological and cardio-pulmonary ages it has been demonstrated that these indices can be treated as the definite predictors of earlier death. Area of application: public health care, medical education (physiology).

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