Severynovs'ka O. The mechanism of the realization of adaptation-compensation reactions of an organism in conditions of action ecopathogenic factors

The dissertation is devoted to studying of molecular and functional mechanisms of infringements and the developments of adaptation-compensation reactions at a molecular level and at the level of an organism, both at separate, and at joint action of the factors of the irradiation-chemical nature, and also an opportunity of the use of natural preparations of Spirylina platensis and beer pollen for the correction of these infringements. It has been determined that according subchronic influence of the doze of an irradiation raised in comparison with a background level an organism answers completely, involving all possible resources. Among priority reactions there is maintenance of balance of active and passive streams K+ on membranes of excitable cells, and also stimulation erytropoez, that is necessary for preservation of homeostasis of all an organism. At the action of heavy metals the majority of the parameters of the condition of erythrocytes depends on their quantity, adaptation occurs inside the system. The salts of heavy metals, changing osmotic resistency of membranes neurons cause development of irre-versible changes in ion-transport system in the cells of a bark of a brain that is the reason of occurrence of an intense condition. The com-bined irradiation-chemical influence is accompanied by mutual easing of separate effects.