Zamaziy A. Hypoxy in newborn calves and its corrections

The dissertation is devoted to studing hypoxy in newborn calves and grounding its treatment by using the suggested biologically active preparation “Surfact ZKF”, containing a high amount of hormones, macro-, microelements, amino- and fatty acids. It has been found out that 19.05 percent of newborn calves are born with the signs of hypoxy and 36.70 percent – with immature surfactant lung system (SLS). The scheme of diagnostic tests with the aim of determining “the maturity” of SLS of new born calves and functional state of the organism has been suggested. It has been proved, that changes in the process of haemopoesis (increasing the number of erythrocytes in blood) the content of haemoglobin, oxygen volume take place as adaptation processes. Hypoxy of calves is accompanied by leucocytosis, thrombopeny, slower renewal of haemolitical indices. Considerable decreasing the amount of amino acids in blood and fetal fluid in hypoxic calves has been noticed because of glucoplastic, lipoplastic, irreplaceable, replaceable (ones). Macro- microelementary composition of liquids of homeostatic organization level in newborn is characterized by hyposodiuminuria and hypercalciuminuria. Under the influence of hypoxy, the content of the main macro- microelementary components of breathing chain and haemopoesis (Fe, Cu, Zn, Co) in blood and fetal fluid decreases. Because of hypoxy the total part of phospholipid fraction of amniotic liquid, lipid and acid composition of blood and fetal fluid of calves is reduced. The processes of peroxide lipid oxidation are activated under the influence of hypoxy. This is accompanied by decreasing the content of unsaturated fatty acids, increasing the coefficient of blood and calves fetal fluid saturation. It has been clarified, that under the influence of hypoxic factor action in liquids of homeostatic level of newborn calves organization, activation of the processes of lipid peroxidant oxidation takes place, antioxidant organism protection is reduced. The processes of lipoperoxidation prevail in haemolizates of erythrocytes. The algorithm of actions and schemes of treatment with the help of biologically active preparation “Surfact - ZKF” have been developed and recommended for correction and treatment of hypoxy in newborn calves. The usage of the given preparation in complex allows to increase safety of hypoxic calves and to receive from 7.62 to 8.12 hryvnyas profit per cow hryvnya of expenses.