Gorsha O. Complex system of estimation and correction the physical methods of disregulation states physical methods for the motor transport drivers

Object of study: 330 motor transport drivers and 129 children with cerebral palsy. Purpose of study: to develop criteria for evaluation of dysregulative states in motor transport drivers on the base of vegetative balance, adaptive resources of their organism and humora-hormonal and metabolic regulation mechanisms study for the pathogenesis ground of their correction by physical factors. Methods: clinical, laboratory, biochemical, cytochemical, morphological, instrumental, mathematical analysis. Theoretical and practical results: there are established pathogenesis mechanisms of biochemical link violations of the nervous system regulatory function of primarily functional and primary organic origin; are given the supplemented ideas about the physiology and pathophysiology of professional tiredness and "burnout" formation, it is found that the complex impact of the professional environment adverse factors for motor transport drivers leads to a progressive and stage by stage development of dysregulative states. A diagnostic algorithm for estimation of the dysregulation stages depending on the vegetative dysregulation, humora-hormonal and metabolic disorders, and disorders of adaptation mechanisms in motor transport drivers is created. Physiotherapy facilities for correction motor transport drivers dysregulated states are designed and reasonable indications for their differential use are grounded. Novelty: first proved that the complex influence of the professional environment adverse factors on motor transport drivers leads to a progressive development of dysregulative states depending on the duration of their professional experience. A conception of the pathogenesis dysregulative echelon of the primary functional disorders formation under the high effort conditions of work, as the main mechanism that leads to the integration function of the central nervous system disruption and causes the characteristics and stability of the morphological and functional damages is formed. It is shown that the primary organic genesis of the nervous system regulatory function violations leads to development of persistent disorders in exchange of humora-hormonal and metabolic regulation systems (catecholamines, nitric oxide and uric acid). The efficiency of the physical factors use for improvement of the regulatory systems trophicity and interactions in the complex rehabilitation of patients with disorders of different genesis dysregulative disorders is proved. Degree of implementation: articles, abstracts, patents, guidelines. Sphere of use: medicine.