Golovko S. The role of innovative technologies in the perioperative diagnosis, surgical treatment and rehabilitation of patients with benign prostatic hyperplasia

The dissertation is devoted to the problem of improving the results of treatment of benign prostatic hyperplasia. In our study, we investigated the current status of monopolar TUR, open prostatectomy and transurethral innovative methods used most often, including bipolar TURP, potassium-phosphate-tytanil laser vaporization of the prostate and lithium-tryborate laser vaporization on the analysis of functional outcomes and complications associated with traditional and minimally invasive methods of treatment. Our analysis demonstrated the statistically significant relative effectiveness and overall safety of the innovative technologies when compared to the traditional surgery. The number of complications (safety profile) was different for each conventional transurethral technology, used in the surgical treatment of clinical BPH.The conducted histological studies have confirmed that during photoselective vaporization there is no pathological photothermolysis with heating large amounts of prostatic tissue. Intraoperatively, no significant coagulative necrosis or edemas of the surrounding tissues was received. The action of "green laser" is limited in depth, and as a result of vaporization of the prostate, no long-term rejection of necrotic tissue or prolonged inflammation was seen.For the first time in the experiments on animals there was developed the method of seamless connection of urinary bladder tissue by means of electric welding of the living tissue, which allows to safely and tightly connect the tissues of the urinary bladder during surgical intervention. The application of electric welding on the sectional urinary bladder and during the open adenomectomy allowed to perform complete sealing of the wall, to use less volume of suture material, to reduce the duration of the operation.