Volkov O. Strategies of cognitive function saving during anesthesia of the cesarean section

This thesis is dedicated to the protection of cognitive functions in anesthesia caesarean section. Established that uncomplicated pregnancy provide light cognitive dysfunction. Markers of systemic inflammatory response (IL-6, IL-10) in postoperative CS with dependence on the method of anesthesia and associated with changes in cognitive function in general and especially memory and control functions. During anesthesia maintenance BIS in IA are within normal limits, when it exceeds the limit TIVA 60. Low bispectral index under general anesthesia cesarean worsen cognitive function. Inhalation anesthesia with Sevoflurane reduces intraoperative analgesia needing on 41.2-50.4% versus TIVA and on 17% prescriptions opioids after cesarean section. Provided methods of anesthesia do not affect the status of newborns and uterine contractions. Cognitive functions normalize by 28th day after cesarean section under IA and SA. At the same time 35.3% (infusion) - 39.3% (bolus) of mothers kept light cognitive impairment after CS under TIVA even by 46th day after surgery.