The object of research - adaptation of technologies for growing grain crops and soybeans on irrigated lands of the Southern Steppe of Ukraine. The goal - was to substantiate and develop the scientific basis for the formation of adaptive technologies for growing cereals and soybeans on irrigated lands, based on the rational use of water resources Kakhovka and Ingulets irrigation systems, biological potential of new varieties and hybrids of crops, optimization of technological methods and technological methods and techniques taking into account changes in the bioclimatic potential of the Southern Steppe zone of Ukraine. Methods - general scientific (experiment, analysis, deduction, observation.) and special (field, laboratory, biometric and measuring-weight, statistical, comparative-calculation). Results - are to develop and implement innovative technologies for growing varieties of winter wheat, winter barley and soybeans and hybrids of corn, adapted to regional climate change in the Southern Steppe of Ukraine, which provide high plant productivity under irrigation subject to reclamation requirements. Research materials were used in the development of "Strategy of economic and social development of Kherson region until 2011", 8 scientific and methodological and 8 scientific and practical recommendations for innovative agro-technological methods of growing winter wheat, winter barley, corn and soybeans on irrigated lands of the Southern Steppe of Ukraine. The research results were tested and implemented in production conditions on irrigated lands of agricultural enterprises: winter wheat on the area of 39.3 thousand hectares, winter barley - 5.6, corn for grain - 2.0 and soybeans - 26, 7 thousand hectares. The novelty of the results lies in solving an important scientific problem in the development of scientific bases for the formation of adaptive technologies for growing cereals and soybeans to climate change in the Southern Steppe of Ukraine by substantiating the methodological basis for realizing the biological potential of new varieties and hybrids and agroecological resources. The results of long - term researches are generalized and features of water consumption and efficiency of water use by crops of winter grain crops, corn and soybeans under different conditions of moistening and elements of technologies of their cultivation are scientifically proved. Mathematical models of irrigation regime parameters and efficiency of FAR use by crops are scientifically substantiated and separate elements of their cultivation technology are optimized, which provide high payback of irrigation water, costs of financial and energy resources. Scientific value - based on the results of generalization of long-term experimental data in irrigation and regional climate change, adaptation of grain and soybean cultivation technologies was performed, mathematical modeling was performed to establish the dynamics of production processes and patterns of yield and quality of studied crops depending on moisture conditions and agrotechnological factors. Sector is agriculture.