Polishcuk I. Phytochemical study of raspberries and the creation of new drugs based on it.

In the dissertation work, solutions of scientific problems on the phytochemical study of the raspberries fruits and the creation of new medicines on their basis are given. Quantitative determination of the main groups of phenolic compounds by spectrophotometry showed that 96% ethanol is the optimal extractant for the preparation of drugs based on hydroxycinnamic acids, for the extraction of other groups of phenolic compounds it is better to use 70% ethanol solution. 83 biologically active substances belonging to phenolic, triterpene compounds, di-, tricarboxylic fatty acids and amino acids were identified qualitatively and quantitatively in raspberry fruits. 72 of them were not previously found in raspberry fruits. Pharmacological studies have shown for the first time that the juice of raspberries is a carrier of immunological action, affecting lymphocytes It was first determined that raspberry extract inactivates type 5 adenovirus and influenza A (H1N1) pdm virus. It was first determined that the extract of raspberry fruit pomace has an antimicrobial effect on both museum strains of ATCC and clinical strains of bacteria. It was first established that the extract of raspberry fruit pomace was characterized by antifungal action