Kovalchuk O. The morphology of cat pancreas under normal and pathological conditions

The goal of the research: to study the morphology of a cat pancreas in a postnatal period of ontogenesis and its lesions under pancreatitis. The unit of analysis: cat pancreas of clinically healthy cats and under pancreatitis. Research techniques: clinical (overall temperature, pulse, respiration, state of specific organs); hematological (morphplogical – the amount of red blood cells and white blood cells; biochemical – the content of hemoglobulin, crude protein, bilirubin, glucose, α –amylases in a blood serum); echo-sonographical: anatomical (macroscopic structure of a pancreas); histological (microscopic structure of a pancreas); morphometrical (determination of absolute and relative indices of a pancreas as well as its structural and functional units) and statistical (digital data handling aimed at revealing the probability of indices changes). The theoretical results are based on the development of the scientific recommendations (on the results of a thesis work) on the pathomorphological diagnostics of a cat pancreas under pancreatitis. The working knowledge represents some practical significance as to cat pancreas morphology in clinically healthy cats, under acute pancreatitis progression and under its chronocity. This knowledge updates the contemporary view of a morphofunctional characteristics of a cat pancreas in a normal state and under the pathological process development. It allows to reveal in detail and to comprehend the aspects of a mechanism of the disease progression as well as to add some new information as to the changes which were revealed in sick animals. The novelty of the research: the clinical and biochemical status, macro- and microscopic structure, organo-, hysto- and cyto-morphometric indices of a pancreas of clinically healthy cats of different age-groups, under acute pancreatitis progression and under its chronicity have been established. It allowed to reveal and elucidate some pathomorphological changes in cat pancreas under pancreatitis, to show some pathogenetic aspects of a disease as well as to update the information about the intra vitam and post mortem differential disease diagnostics. The rate of implementation: the results of a thesis work have been implemented into the scientific and research work and are used in teaching and learning activities at the department of systematic and pathological anatomy of farm animals of Dnipropetrovsk State Agricultural and Economic University; at the department of systematic and pathological anatomy of Kharkiv State Zoo-Vetrinary Academy; at the department of veterinary-sanitary inspection, animal products hygiene and pathological anatomy named after Zagayevskyi I.S. of Bila Tserkva National Agricultural University; at the department of anatomy and hystology named after Kovalskyi P.O. of Bila Tserkva National Agricultural University; at the department of anatomy, hystology of pathomorphologies named after Kasyanenko V.G. of National University of Life and Environment of Ukraine; at the department of pathological morphology and judicial veterinary of Lviv National University of Veterinary Medicine and Biotechnologies named after Izhytskyi S.Z.; at the depertment of anatomy of systematic and pathological physiology of animals of Summy National Agricultural University; at the department of systematic and pathological anatomy of Poltava State Agricultural Academy; at the departmment of hygiene and animal breeding of Vinnytsia National Agricultural University; at the department of systematic and pathological morphology and judicial veterinary of Odessa State National University. The efficiency: integrated research techniques – hematological, anatomical, pathological-anatomical, hystological, morphometrical, statistical ones allowed to substantiate and to specify the patomorphogenesis of pancreatitis in cats depending on acute or chronical disease progression. A sphere of usage: the scientific insights which have some theoretical and practical significance and were recommended for introducing in speciality 211 “Veterinary Medicine” in the field of knowledge 21 “Veterinary Medicine” were received in the course of investigation.