Voskobojnykova G. Elaboration of composition, technology and research of soft officinal forms done of officinal raw material of Pine ( Pinus silvestris)

This thesis is devoted to problems of elaboration of optimum composition and technology of soft officinal forms ( suppository, liniment, extractive ointment ) done of officinal raw material of Pine. Facts connected with elaboration and analysis of composition of soft officinal forms are submitted for consideration. Biological active substances from raw material of Pine (terebinthin-balsam buds neebles ) with additional substances and racionalbase-bearer are united in these ferms. Research of problems of standartisation of officinal raw material of Pine has already carried out. Apart well-known pharmacopoeic methods of standartisatio of therebinthin, buds of Pine, stendartisation by gnantitative contents of ?-pinen by means of gas-liguide chromatography, by guantitative contents of tannin by means of titration, byguantitative contents of carotenoid in re-computation of ?-carotene by means of spectrophotometric. Compositioon and technology of explored officinal forms are grounted the oretically and confirmed practically on the basis of biofarmaceutics, reological and biological research. Inversication of period of validity of given officinal forms has alreabycarried out.