Antonyuk S. Myocardium morphofunctional changes in the severe thermal trauma and after sorption detoxication

The thesis is devoted to studying of the myocardium morphofunctional changes in the severe thermal trauma and after sorption detoxication. It is revealed that severe burn causes remarkable structural changes in myocardium, their character and expressiveness depend on the stage of burn disease. In the shock and early toxemia stages slight destructive changes are developing in cardiomyocytes and structural components of microcirculatory bed and they are accomanied by intracellular regeneration,hyperplasia and hypertrophy of organelles. In the late toxemia and septicotoxemia stages adaptive compensatory reactions frustration has become and deep destructive changes are developing in myocardium. It is revealed enterosorbent enterosgel usage to stimulation of the intracellular regenerative processes and improving the morphofunctional condition of cardiomyocytes and microcirculatory bed.