Dvornyk A. Studies on the antimutagenic properties of the extracts from the biomass of some medicinal plants' cultured cells

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0401U002962

Thesis Registration Form

0401U002962.pdf

Applicant for

Specialization

  • 03.00.15 - Генетика

30-10-2001

Specialized Academic Board

Д 26.202.01

Essay

Antimutagenic properties of aqua-alcoholic extracts derived from the biomass of cultured Panax ginseng, Polyscias filicifolia, Rhodiola rosea, Ungernia victoris cells have been studied in two prokaryotic systems. In Ames test the extracts under study failed to affect the level of spontaneous mutants of S.typhimurium TA 98 and TA 100 and effectively inhibited the chemically induced mutagenesis. To reveal the antimutagenic effects of the preparations use of Escherichia coli - bacteriophage l system was proposed. In this test-system were demonstrated extracts protective activities, which by the intensity of the protective effect could be arranged in a row as follows U.victoris > P.ginseng > P.filicifolia.

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