Kushnir S. Использование фибронектинзаместительной терапии для коррекции иммунноэндокринного дисбаланса у больных хроническим обструктивным бронхитом

Research subjects: 148 patients with chronic obstructive bronchitis Research objectives: the scientific substantiation of the usage and the estimate of clinical efficiency of the application of of heparinized one-group fresh-frozen plasma as fibronectin-replacement therapy was given in patients with chronic obstructive bronchitis Methods: medical methods of investigation of patients with lung diseases; statistic methods. Theoretical and practical results: the complex estimation of peculiarities of fibronectin functional fusion, thyroid hormones, thymic factors and cellular immunity during progressive course of chronic obstructive bronchitis was given, and presence of endocrine (thyroid hormones) misbalance was revealed in patients with III stage of chronic obstructive bronchitis severity Novelty of introduced: of the usage of heparinized one-group fresh-frozen plasma as fibronectin-replacement therapy and modulator of immunoendocrine system was given in patients with III stage of chronic obstructive bronchitis severity during exacerbation. Implementation degree: articles, theses Sphere, sector of implementation: medicine