Ostash B. Genetic control of several steps of landomycin E biosynthesis in Streptomyces globisporus 1912.

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0403U003108

Applicant for

Specialization

  • 03.00.15 - Генетика

25-09-2003

Specialized Academic Board

Д.26.202.01.

Essay

Streptomyces globisporus 1912 gene cluster for antitumor antibiotic landomycin E biosynthesis (lnd) has been identified and sequenced. The roles of six structural lnd genes and regulatory lndI gene have been studied. Novel landomycins with altered aglycon structure have been obtained for the first time.

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