Prilutskiy A. Structural organization of trophicity of an enamel organ of tooth germs of the human in embryogenesis

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0404U002786

Applicant for

Specialization

  • 14.03.01 - Нормальна анатомія

17-06-2004

Specialized Academic Board

Д 64.600.03

Essay

Subject of investigation: dental germs of lactic cogs of three and six-month germs of the person. Objectives: to straighten out a principle of structural organization of microcirculatory processes ensuring a histogenesis of solid tissues of lactic cogs at early stages of prenatal development. Methods of investigatin: manufacturing of semithin shears with further analysis them with the help of a light microscopy. Theoretical and practical value of the obtained findings: the outcomes of system analysis of dental germs in an incipient state of a histogenesis of solid tissues of a cog can be extrapolated in area of an odontology, as the theoretical basis for comprehension of reasons of every possible anomalies of development of cogs, and also for exact treatment of a pathogeny of the different forms of a lesion of solid tissues of a cog. Besides the obtained data and the illustrative material in a condition is essential to deepen and to expand the contents of the educational program on stands of anatomy and histology at analysis of a constitution and development of cogs of the person. Scientific novelty of the obtained results: the priority data about features of structural maintenance of exchange processes between a blood and internal epithelium of an enamel organ at the stage of it differentiation in enameloblasts both first depositions of a dentine and enamel Are obtained. Alongside with it the padding information is obtained permitting it is essential to expand positions, available in the literature, about a histogenesis of a pulp and solid tissues of a cog. Is concretely established, that the outside epithelium of an enamel organ is in close structurally functional relationships with exchange microvessels of hemomicrocirculatory channel which was gobed up in connective tissue stroma of a tooth saccule. Thus, an endothelium wall of exchange microvessels, intercellular substance of a tooth saccule and layer of an outside epithelium are in the basis of formation of hemato-cellular barrier arranged on pathofthe transport of a filtrate of a blood plasma in colloidal contents of a pulp of an enamel organ. Runways of a filtrate of a blood plasma are intercellular slot in an outside epithelium of an enamel organ. For period from three about six months of embryonic development by a native born image the structural organization of hemomicrocirculatory channel of crown part of an enamel organ changes, that conducts to formation of a portal system of blood stream, in which one the exchange microvessels of an outside epithelium are in-sequence between arterioles and capacitive venulis. In bridge with above-stated transformation is epithelial - microvessels relationships of the process differentiation of an internal epithelium of an enamel organ in a layer of enameloblasts is completed, that expresses in transformation of two-row arrangement of cells in single-row, polarly oriented cell-like association. Degree of an intrusion: the pieces of a thesis are inserted in educational process on stand of normal anatomy of Lugansk state medical university, stands of anatomy and histology, cytology and fetology of Ukrainian medical stomatological academy, stands of anatomy both topographical anatomy and operating surgery of Bukovina state medical academy, stand of normal anatomy of medical faculty of the Sumy state university and stand of anatomy of the Kharkov state medical university. Sphere of usage: anatomy, histology.

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