Khokhlenkova N. Development technology and research of ointment "Prolidoxyd"

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0404U004623

Applicant for

Specialization

  • 15.00.01 - Технологія ліків, організація фармацевтичної справи та судова фармація

03-12-2004

Specialized Academic Board

Д64.605.01

Essay

The thesis is devoted to creation of a new medicinal preparation in the form of ointment on the basis of substance of a natural origin - phenol-hydrophobic propolis preparation (PHPP). Based on physical-chemical, technological, biopharmaceutical and biological researches results the optimum composition and rational technology of ointment "Prolidoxyd" have been developed. Complex of quality parameters has been chosen and methods of the analysis of ointment have been developed. The ointment "Prolidoxyd" properties and its stability during a storage have been studied. Pharmacokinetic researches of "Prolidoxyd" ointment have been carried out. By biological researches a specific activity and harmlessness of "Prolidoxyd" ointment have been established. The drug developed is offered for local treatment of purulent wounds in I phase of wound process, burns of mild and mean degree, inflammatory infiltrates.

Files

Similar theses