Kolisnyk I. Morphofunctional characteristics of adrenal glands and their nerves at norm and under the influence of phosphorus-containing detergents (anatomical experimental study)

Object of the research: Morphofunctional characteristics of human endocrine glands and their nerves at norm and under the influence of some exogenous factors. Purpose of the research: To study morphofunctional characteristics of human adrenal glands and structural organization of their nerves at micromacroscopic and microscopic levels; to study the structural changes of the adrenal glands and their nerves under the influence of phosphorus-containing detergents in experiment with white rats. Methods of research: Morphological, histological, experimental morphological, electron microscopic, histochemical, biochemical, statistical. Practical significance of the obtained findings: The anatomical schemes of the variants of paravasal nerves of the adrenal glands can be a structural basis for improvement of the existing and working out new methods of surgical interventions on the above glands. This ai a theoretical basis for further morphological and topographic studies in clinical anatomy, for active in-vestigation in neuromorphology, for publication of textbooks in normal clinical anatomy. The findings of the research can be used in toxicology, research laboratories as well in the teaching process at departments of human anatomy, pathology, histology, biochemistry, general hygiene, occupational diseases, forensic medicine. Patent "A method of ultramorphotopometry" can be used in morphological, pathology, forensic medicine, toxicology studies. Scientific novelty: Macromicroscopic specimens were used to create the original anatomical schemes of variants of paravasal nerves of human adrenal glands. For the first time, intratruncal structure of paravasal nerves of the adrenal glands was studied in association with the variants of the vessels supplying the organ. For the first time, great experimental material was used to determine the complex of rearrangements in the adrenal glands which develop in the experimental animals under the influence of a new phosphorus-containing detergents. Degree of introduction: The findings of the research were introduced into the teaching process at departments of anatomy and general hygiene (Kharkiv State Medical University). Sphere of application: Medicine, neurology, endocrinology and toxicology.