Kunskaya K. Antenatal etiology and pathogenetic's links of toxic dyspepsia by new born calves, their correction

The object of research: toxic dyspepsia of the calves The purpose of research: study of influence of pregnant cow's feeding on physiological full value of newborn calves and biological quality of milk; to work out the effective methods of correction of the basic pathogenesis parts of calve' toxic dyspepsia. Methods of research: clinical, biotechnical (analysis of cow' feeding), morphological of blood structure (erythrocytes, leucocytes), biochemical (determination of hemoglobin, total protein, protein fraction, total calcium and inorganic phosphorus, reserve alkalis, carotene, creatinine and urea, immunoglobulins, potassium and sodium), determination of hematocrit and dysproteinemia on sulema sample' resulting; the investigation of colostrum (total protein, immunoglobulins, titration' acidity). Scientific novelty: it is theoretical proved and experimental argued the opportunity of reliable preventive of neonatal calve' dyspepsia at expense of full value cow' feeding during all pregnancy and not just in dry period. The biological chain is established: a forage - metabolism in cows - quality of the colostrum - calve' stability to dyspepsia. For correction of the basic parts of pathogenesis of the toxic dyspepsia in newborn calves is worked out and clinical tested electrolytic-antitoxic complex "KET", match optimum doses of it's components, especially potassium chloride. It is established that more resistance to dyspepsia calves in AR Crimea are born from cows which were inseminated in February-March. The receiving of full value calves is provided by keeping pregnant cows on rations with large part of green grass (63-72 per cent on energy) during period of the fetal' growing and development. The full value first and second colostrum is characterized with: protein - accordingly 17.88-26.5 and 14.0-23.0 per cent; immunoglobulin - 45.8-89.9 and 41.8-64.3 mg/ml; colostrum acidity - 39.7-49.7 and 32.0-43.0?T. The basic blood values which characterize the calves' resistance to dyspepsia are total protein (59.0-62.3 g/l) and immunoglobulin 21.8-27.1 mg/ml). It is established high efficacy of "KET" (as alone and in complex with enzyme medicine "Festal") for treatment of newborn calves with toxic dyspepsia. The efficacy is 3.7 grn. for 1 grn. of expenditure. Suggested: the preventative of gastrointestinal diseases in newborn calves. For treatment of toxic dyspepsia in newborn calves is worked out electrolytic-antitoxic complex "KET". The results of investigation are offered to use in veterinary medicine practice for treatment and prevent of gastrointestinal diseases in newborn calves, studying these diseases in agrarian universities III-IV levels of accreditation, publishing reference and teaching books on the diseases of offspring animals; Inculcated: the results of investigations are included in "The methodical recomendations on diagnosis, preventative and treatment of dyspepsia in newborn calves", which are approved by the Chief of veterinary medicine Board of AR Crimea 14.06.2004. The scientific position of dissertation are used for prepearing of veterinary medicine doctors and masters, and also during post graduated studying of veterinary specialists; Using area: Veterinary Medicine.