Korzh G. Clinico-pathogenetic peculiarities of clinical course and treatment of chronic obstructive lung diseases in cases of Chlamydia pneumoniae contamination

The thesis lists sydromic peculiarities of clinical course of chronic obstructive lung disease in cases, when patients were infected by Chlamydia pneumoniae. The author examines changes in immune response, protective barrier of mucous tunic of respiratory tract and system of lung surfactant depending on clinical course and degree of pathology severity. The thesis elucidates pathogenetic aspects of formation and progress of chronic obstructive lung disease depending on identification or absence of Chlamydia infection. The author analyses improvement of complex therapy of chronic obstructive lung disease in cases, when patients were infected by Chlamydia pneumoniae. Such improvement is caused by the differentiated prescription of treament by prtoteflasid and quercetin. The work demonstrates ist high efficiency in normalization of cooperation processes of lymphocytic population, system of interleukines, endogenous interferons, lung surfactant, and local protection of respiratory tract mucous tunic. It also decreases duration of treatment, facilitates prevention of complications and elimination of Chlamydia infection in organism.