Moyiseyenko O. Тhe morphological changes and readaptable transformations in the bones of the skeleton at the thermal affection under the influence of the salts of the heavy metals on the organism in the various age periods (anatomy-experimental investigation)

Object of the research: thigh-bone and pelvic bone, first lumbar vertebra of laboratory rats. Purpose of the research: Investigation of morphological | changes|changing| of the bones of the skeleton at the thermal affection under of influence of the salts of the heavy|difficult| metals on the organism in the various age periods were stadied. and triel to correct revealed changes with „Calceminium Advance” medicine. Methods of research: Osteometry, light optical microscopy, morphometry of the cells of bone and cartilage tissue histological specimens, quantitative evaluation of the bones chemical composition indices, statistical treatment of numerical data. Practical significance of the obtained findings: Obtained findings could be used for morphological substantiation of pathological changes|changing| in a skeleton in the clinics of traumatology and orthopaedy, combustilogy|, paediatrics, gerontology, in judicial medicine. Scientific novelty of the obtained findings: The dysplasia, the histological alteration|realignment| and the chemical composition of the bones at the thermal affection under the influence of salts of heavy|difficult| metals on the organism, which|what| shows up diminishing of linear sizes|dimensions| of bones, the violation of the structure|building| and the morphometric indexes of the growing | cartilage, the compact and spongy matter of tubular, the spongy and the flat bones of animals. Diminishing of the bones’mineral saturation and the level of calcium is accompanied by an overhydratation and the accumulation of the metals within the organism. The most of these changes|changing| were found at the animals of young | age. Using the preparation „Calceminium Advance” during month allowed to decrease the negative changes|changing| in the bones of the skeleton at action|act| on the organism of explored exogenous factors at the animals of young | and mature| age. Degree of introduction: The findings of our research were introduced into the teaching process at departments of human beinganatomy, pathological anatomy, surgery, traumatology and orthopaedy in higher educational establishments of Ukraine (Ivano-Frankivsk city, Simpheropil city, Ternopil city, Lugansk city, Kharkiv city, Melytopol city, Sumy city). Sphere of application: medicine, traumatology, orthopedics, combustilogy|, paediatrics, gerontology, in judicial medicine.