Halinska V. The course of bronchial asthma at the people with Chlamydia pneumoniae infection

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0407U001531

Applicant for

Specialization

  • 14.01.27 - Пульмонологія

26-03-2007

Specialized Academic Board

Д 26.552.01

State organization “National Institute of Phthisiology and Pulmonology named after F.G. Yanovsky National academy of medical sciences of Ukraine”

Essay

Object of research - bronchial asthma. The purpose - the establish of frequency and degree of Chlamydia pneumoniae infection in patients with asthma, to study the features of clinical flow of asthma in the case of Chlamydia pneumoniae infection. Methods of research - laboratory-clinical, functional and serologic in order to reveal the titre of antibodies Ig G to Chlamydia pneumoniae, polymerases chain of reaction to reveal genom Chlamydia spp in sputum, pharmaeconomical analysis of direct medical expenditure in the time of diagnostic Chlamydia pneumoniae infection. Results - the frequency and the degree of Chlamydia pneumoniae infection have been studied in patients with bronchial asthma. It has been established by different serologic test-systems that frequency of positive title of antibodies IgG to Chlamydia pneumoniae at the bronchial asthma patients is the same as healthy people. Physical examination, laboratory and functional test results at severe bronchial asthma patients with Chlamydia pneumoniae have not been significantly different from severe bronchial asthma patients without ones. In isolated cases under the conditions of presence frequent, infectional dependent exacerbations is observed the effect of special antibacterial therapy. Area of application - pulmonology, therapy.

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