Sorokopud O. Prognostic factors of the community-acquired pneumonia clinical course and assessment treatment efficacy

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0407U003160

Applicant for

Specialization

  • 14.01.27 - Пульмонологія

02-07-2007

Specialized Academic Board

Д 26.552.01

State organization “National Institute of Phthisiology and Pulmonology named after F.G. Yanovsky National academy of medical sciences of Ukraine”

Essay

Object of research - community-acquired pneumonia. The purpose - to propose the diagnostic criteria for prognosing clinical course and assessement community-acquired pneumonia treatment efficacy. Methods of research clinical, laboratorial, instrumental, microbiological and statistic analysis. Results - the community-acquired pneumonia clinical course was analyzed. It was revealed high frequency of hypocholesterolemia, which was associated with severe clinical course, higher C-reactive protein level. Hypocholesterolemia, significant C-reactive protein increasing, low level of cholesterol low-density lipoprotein and apoprotein B are unfavourable for a community-acquired pneumonia clinical course. Treatment efficacy was assessed by inflammatory syndrome and lipid metabolism tests. Complete convalescence associated with decline of inflammatory syndrome tests and increasing to normal total cholesterol. Area of application - pulmonology, therapy.

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