Gromyko O. Antibiotic resistance mutations that influence the biosynthesis of landomycin E in Streptomyces globisporus 1912-2 and nogalamycin in Streptomyces nogalater IMET43360

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0408U001058

Applicant for

Specialization

  • 03.00.15 - Генетика

28-02-2008

Specialized Academic Board

Д 26.202.01

Essay

The dissertation offers the description of approaches towards the construction of highly active producers of antitumor antibiotics landomycin E (Streptomyces globisporus 1912-2) and nogalamycin (Streptomyces nogalater IMET43360). Obtain and characterization of erythromycin, chloramphenicol and streptomycin resistant mutants of high level producing of landomycin E and nogalamycin.

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