Kalashnikov V. Etiological role of conditional-pathogenic microflora, improvement of methods of prevention and therapy of endometritises

Object of research: diseases of cow reproductive organs, nonspecific agents.Purpose of research: study of the role of the conditional-pathogenic microflora in the etiology of cow postnatal endometritis and the development and estimation of the efficiency of the means of immunoprophylaxis and symptomatic therapy of some types of postnatal pathology in cows.Methods of research: bacteriological, serological, clinical, obstetric-gynecologic, pathologoanatomic, biochemical, hematological and statistical.The equipment: thermostate, scales, centrifuge, refrigerator.Theoretical results: application of new means of specific prophylaxis and therapy of the most widespread diseases of cow reproductive organs has been experimentally grounded. Specific composition of dominant microorganisms at obstetric-gynecologic pathologies has been determined.New data concerning the spread of these agents with certain pathogenic, hemolytic, toxigenic, antigenic characteristics has been received. Antibiotic resistance of these agents has been determined.Practical results: method of preparation and and normative documentation on the "Vaccine subunit inactivated for prophylaxis of cow postnatal endometritises" (SS U 24.4-00497087-067:2007), technology of preparation and and project to normative documentation on treatment-and-stimulatory preparation "Uteroton" have been developed. Results of investigations were included into scientific-and-practical publications "Short textbook on veterinary obstetrics and gynecology" and "Manual on veterinary obstetrics".The novelty of work is confirmed by 2 patents.Degree of introduction: package of normative documentation on immunizing preparation "Vaccine subunit inactivated for prophylaxis of cow postnatal endometritis" has been developed. Documentation was approved in the State Department of Veterinary Medicine of Ukraine (SS U 24.4-00497087-067:2007).Field of using: veterinary medicine.