Boyko D. Individualization of the combined therapy of patients with chronic obstructive pulmonary disease I-II stage depending on clinic-immunological variants of current

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0408U002518

Applicant for

Specialization

  • 14.01.27 - Пульмонологія

19-05-2008

Specialized Academic Board

Д 26.552.01

State organization “National Institute of Phthisiology and Pulmonology named after F.G. Yanovsky National academy of medical sciences of Ukraine”

Essay

Object of research - patients with different clinic-immunological variants of current of chronic obstructive pulmonary disease І - ІІ stages. The purpose of research - to verify the basic clinic-immunological variants of current of chronic obstructive pulmonary disease І - ІІ stages and on their basis on dynamics of clinical semiology and parameters of immune system to define efficiency of individualized complexes of therapy, taking into account presence of an accompanying cardiovascular pathology. Scientific novelty - for the first time on a basis cluster analysis have been determined clinic-immunological variants of current of chronic obstructive pulmonary disease І - ІІ stages and the differentiated circuits of optimization of basic treatment of these patients are developed. Results: high efficiency of the developed differentiated circuits of optimization of basic treatment of patients with chronic obstructive pulmonary disease І - ІІ stages is proved. To make good use at patients with chronic obstructive pulmonary disease ІІ stage for treatment mild essential hypertension and pulmonary hypertension І stages an item antihypertensive drug from group of calcium channel blockers dihydropyridine lines - lercanidipine. The technique of diagnostics pulmonary hypertension with use Doppler echocardiography and a spiral computer tomography is scientifically proved. The area of application - pulmonology.

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