Blishcavenko Y. Angioarchitectonics of the human placenta and structure of the placental barrier in norm

The investigation object: structure of the human placenta. The investigation goal: is to receive the pictorial view about angioarchitecture of the umbilical cord and human placenta and to develop the principle of structural organization to its villous chorion. Methods of research: macroscopic, histological, corrosive, immunohystochemical, morphometric. The theoretical and practical importance of the received results: findings considerably broaden knowledge about morphofunctional structure of umbilical-placental blood circulation, can be useful for of prenatal pathology diagnostic practice, for pathologist’s examining placenta to find real causes of antenatal fetal death, different forms of placenta aperiodicity, abnormality of umbilicus-placental blood circulation and inflammatory and dystrophic processes of placenta. In this case our treatise of functional purpose in villous chorion of fibrinoid deserves attention. The scientific novelty of the investigation results: For the first time the descriptivesystematization of umbilicus-placental bloodstream of a man was made. The presence of Hoyer’s canals, which localized in the stem villus of branchy chorion scientifically grounded in the bloodstream of placenta was visually proved. It was scientifically grounded, that at the expense of given Hoyer’s canals the shunting transportation of definite volumes of blood from arterial to venous bloodstream, passing hemomicrocirculational bed of cotyledons, can be functionally done. The facts show, that metabolic process in placenta are executed not only at the expense of terminal links of hemomicrocirculational bed of terminal villus, but due to presence of metabolic blood micro vessels in stem villus pariental allocation, between their thin endothelial sides and the maternal blood there is boundary thin layer of tissue architecture, appropriate to the concept of placental barrier. It was established, that it executed local adhesive bond between closely tangent in the points of contact, preterminal and terminal villusin the range of particular cotyledons and thereby prevented their shift in lacuna space of basal lamina uterus. Branch of usage: medicine, pathological anatomy, normal anatomy, histology, obstetrics.