Povyetkin S. The development of composition and technology and studies of Silybum oil containing suppositories

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0408U004994

Applicant for

Specialization

  • 15.00.01 - Технологія ліків, організація фармацевтичної справи та судова фармація

28-11-2008

Specialized Academic Board

Д64.605.02

Essay

Scientific-methodical approach for creation of Silybum oil containing suppositories for proctological application has been developed. The composition of preparation in form of suppositories has been theoretically and experimentally grounded. On the basis of complex biopharmaceutical, physical-chemical, pharmaco-technological and biological studies, optimal technology and suppositories standardization methods for treatment of the proctologic diseases such as proctit, hemorrhoid, anal crack have been developed. Physical - chemical properties of the investigated suppositories have been studied, methods of quality analysis have been proposed, conditions and terms of storing have been determined. According to pharmacological studies specific activity of the developed suppositories has been proved.

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