Pokotylo O. Development of composition and research of medicines with amino acids and magnesium salts for metabolism regulation of CNS in children

Dissertation is devoted to the development of composition, substantiation of sequence of technological process and research of properties of medical syrups with neurotropic amino acids (glycine, GABA, glutamic acid), vitamin В6 and chloride of magnesium. The complex physicochemical, technological, pharmaco-technological and microbiological research is conducted for the investigation of auxiliary substance and taste properties of medications with sugary base and without it. The technological chart of preparing of the syrups “Magnelong” and “Glutamag” is proved. The basic indexes of syrups quality are offered. The storage conditions and shelf life of the syrups had been proved. The positive influence of syrups on physical and psychical development of laboratory animals were set by the preclinical researches. The draft of specification of Ukraine 15.9-02010741-056:2006 was developed and approved; two declarative useful model patent of Ukraine were taken out.