Popelyuk O. Development and formation of topography of the larynx in early period of human ontogenesis

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0409U003216

Thesis Registration Form

0409U003216.pdf

Applicant for

Specialization

  • 14.03.01 - Нормальна анатомія

28-05-2009

Specialized Academic Board

Д 58.601.01

I. Horbachevsky Ternopil State Medical University

Essay

The thesis is dedicated to the study of peculiarities of laying, development, dynamics of larynx formation in prenatal period of ontogenesis and in new-born children. With the aid of appropriate morphologic methods the formation and syntopic change of oral region components, periods of their intensive and delayed growth, critical periods, variants and probable malformations were observed. It is determined that the germ of larynx appears in embryos 5,0 – 5,5 mm of cranio-caudal length as a ventral protrusion of primary gut on the level of pharyngeal part, being delimited by the wide depression. The reconstruction of epithelium starts on the ventral and lateral walls of the germ of larynx. As a result of the concentration of mesenchyme the formation of laryngeal cartilages occurs: epiglottis – in embryos 11,0-13,0 mm, cricoids – prefetuses 16,0-18,0 mm, thyroid – prefetuses 19,0-20,0 mm, arytenoids – 22,0-23,0 mm of cranio-caudal length. By the end of fifth – the beginning of sixth month the cartilages of the larynx obtain their definitive shape. The end of embryonic and the beginning of the prefetal period of human ontogenesis should be considered as the critical periods of the development of the structures of larynx.

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