Ryhlik S. Neuron-glial-capillary relationship in ventrolateral group of nuclei of human diencеphalon.

The investigation object: ventrolateral group of nuclei of human thalamus in different age groups (30-86 years). The investigation goal: to define neuron-glial-capillary relationship of ventrolateral group of nuclei of the human brain thalamus. Methods of research: macromicroscopic, microscopic, morphometric, variation statistics methods, factor and correlation analysis. Theoretical and practical value of the obtained results: the practical value of the work is in the development of morphological criteria for research and evaluation of neuron-glial-capillary relationship of ventrolateral group of nuclei of the human brain thalamus, which can be used in the pathological anatomy practice in the verification of diagnosis, at the opened and stereotaxical operating access to the subcoral structures, for the intraoperative biopsy in the neurosurgical and neurological clinics. On the basis of study of morphological and morphometric features of neuron-glial-capillary relationship of ventrolateral group of nuclei of the human brain diencephalon was developed a method of preparation of biological object (patent № 49545А Ukraine, 7G01N1/30, bulletin №9 from 16.09.02). The morphological features of ventrolateral group of nuclei of the human brain diencephalon, that we have got are used in the scientific research and education process. Scientific novelty of the obtained results: morphological and morphometric data about neuron-glial-capillary relationship in ventrolateral group of nuclei of the human brain diencephalon have been got for the first time. It was developed a method for determination of borders of human thalamus nuclei with the use of colouring on L. Amador. On the base of the developed counting method of closeness of neurons, glia cells, capillaries are set the quantitative descriptions of nervous tissue components in the ventrolateral group of thalamus nuclei at the persons of a different sex and age. It was shown, that with the increase of an age a closeness of neurons and capillaries decreased for certain and a closeness of glia cells was grown. It was shown for the first time, that neuron-glial-capillary relationships of ventrolateral group of nuclei of the human brain thalamus in the men and the women were similar and do not depended on the side of a brain. The length of the intercomissural line does not affect a closeness of distributing of tissue components in the ventrolateral group of nuclei of thalamus. The degree of implementation: basic data are implemented in the education process at the departments of histology, cytology and embryology, normal human anatomy in the high medical Ukrainian education establishments of Kharkov, Lugansk, Simpferopol, Poltava.