Davibida N. Morpho-functional characteristic of the long bones at the different regimes of the motive activity in an age-old aspect

Application of unique methodical approach and complex of adequate methods of research on large homogeneous experimental material allowed to find out conformities to the law of morpho-functional transformations of structure of long bones of animals which take place in the conditions of the different modes of motive activity in the different age groups. The intensive physical loadings cause inhibition of growth and osteoclastic resorbtion of humeral bones tissue and their structural elements in the animals of young and mature ages. In the animals with the expressed senile changes considerable destructive changes in all departments of humeral bones were observed. Morphometric research methods allow to assert about the maximal motive changes of bones in the group of old animals and minimum at the animals of mature age. The moderate physical loadings are the factor of inhibition of involutive changes in humeral bones. In the group of young animals the processes of narrowing of plate and multiplying activity of osteoblasts were observed, that mediated showed up multiplying the sizes of bones and their structure at experimental animals. In the group of animals with the expressed senile changes inhibition of mineralization of bone is noticed. It is set that the effect of action of the different modes of motive activity on the processes of morphogenesis depends on age and also intensity and duration of the physical loadings.