Pavkh O. Creating of composition and development of technology of nasal ointment based on herbal tinctures and essential oils.

The thesis is devoted to the theoretical and experimental foundation of composition and technology creation of a semisolid dosage form as emulgel based on herbal tinctures and essential oils for the prevention and treatment of inflammatory diseases of the nasal mucosa. The optimal composition and appropriate technology of a semisolid dosage form as emulgel with herbal tinctures and essential oils is scientifically proved on the basis of technological, physical-chemical, biopharmaceutical, rheological and microbiological researches results. The main drug quality parameters and methods for their determination are investigated. The emulgel stability during its storage is studied. Anti-inflammatory, antimicrobial, and reparative activity of the developed emulgel "Rhinitostop" is established on the basis of pharmacological.