Krasovs'ka I. Development of composition, technology and research of complex antifungal and antimicrobial action spray

A scientific-methodical approach has been proposed for creation of spray preparations containing combination of antifungal and antimicrobial substances for treatment of skin pyoinflammatory diseases caused by opportunistic and patogenic microorganisms and fungi. On the basis of complex biopharmaceutical, physical, chemical, pharmaceutical, technological and microbiological researches theoretically and experimentally the composition has been grounded and rational technology has been proposed for "Micosil-Stoma" spray with antimicrobial and antifungal activity, containing terbinaphine hydrochloride and benzalconii chloride. For active components antimicrobial and antifungal activity enhancement formaldegide solution has been included. Ethanol, propyleneglycol and polyethyleneoxide-400 has been included as auxiliary substances. Polyvinylpyrrolidone 1 % which presence prolongates action of active substance has been included as thickener