Object of research - diseases of the pancreas in dogs. Aim - to explore little-known links of the pathogenesis of pancreatitis in dogs, improve its diagnosis in acute and chronic forms based on clinical, sonographic and laboratory methods, develop effective treatment schemes animals. Research methods and equipment - clinical, clinical blood and urine analysis, biochemical, instrumental (sonographic), biometric. Theoretical and practical results - the established scheme of pathogenesis of pancreatitis in dogs with acute and chronic forms based on the results of their research and modern science literature. Experimental and theoretical application of indicators of connective tissue in the blood serum middle molecules, amylase-kreatyninovho ratio and other biochemical parameters in genetic pathogenesis and diagnosis of pancreatitis in dogs. Established sonographic criteria and limits of biochemical parameters in serum and urine of clinically healthy and sick dogs pancreatitis. Differential diagnostic criteria for acute and chronic forms of pancreatitis based on clinical, sonographic and biochemical studies. Proved the efficiency of treatment schemes using dogs diet antieshemic, antispasmodic, membrane, polyvitamins, fermentzamistnyh and other drugs that can reduce mortality, the timing recovery animal with pancreatitis, improve their quality of life. Novelty - set little-known links of the pathogenesis of pancreatitis in dogs with acute and chronic forms, including mechanisms of fibrosis of the pancreas based on an analysis of indicators of connective tissue and the degree of endogenous intoxication. First the diagnostic value of sonographic criteria and indicators of connective tissue metabolism, activity of а-amylase in serum and urine amylase-kreatyninovoho index in the complex diagnosis of pancreatitis in dogs. Developed and experimentally proved effective treatment regimen for dogs pancreatitis. Performance - the results of scientific studies used in the learning process in teaching subject "Biochemistry", "Clinical Diagnosis", "Clinical Biochemistry" and "domestic animal diseases" in the Kharkiv State Academy of Veterinary and Lugansk National Agrarian University, "Clinical Diagnosis", " Clinical chemistry " and " domestic animal disease - in Poltava state agrarian academy, "Clinical Biochemistry" - in the national pharmaceutical, materials used in the thesis in private practice veterinary hospitals "Dog + Cat" Kharkiv. Field (industry): the use of veterinary medicine.