Zoz O. The antiviral properties of chemical substances on the equine herpesvirus I type model

Українська версія

Thesis for the degree of Candidate of Sciences (CSc)

State registration number

0411U006548

Applicant for

Specialization

  • 16.00.03 - Ветеринарна мікробіологія та вірусологія

17-10-2011

Specialized Academic Board

Д 26.004.03

National University of Life and Environmental Sciences of Ukraine

Essay

The materials on the biological properties of the three reference strains of equine herpesvirus of type I and change their infectious properties in different biological systems (cell cultures inoculated animal). An initial scheme of screening antiviral agents in vitro system. It cytotoxic and antiviral properties of new synthetic derivatives of porphyrins and well-known pharmaceutical drugs (acyclovir, amizonum and indomethacin) and their compositions of type I HC in the system in vitro. The ratio of experimental data cytotoxicity of chemicals in the in vitro and results of acute toxicity in the system in vivo.

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